Joanne Kurtzberg, MD, Duke University, Durham, NC, describes ongoing research evaluating the potential of umbilical cord blood infusion in pediatric patients with cerebral palsy. A randomized Phase II trial (NCT01147653) indicated that the infusion of autologous umbilical cord blood (UCB) at a dose of 25 million cells per kilogram or higher resulted in improvement in gross motor function. In addition, the open-label Phase II ACCeNT-CP trial (NCT03473301), which compared a single high dose of allogeneic UCB with repeated infusions of cord tissue mesenchymal stromal cells (MSCs), demonstrated that UCB infusion improved motor function and has prompted the initiation of a Phase III trial. This interview took place at the 2021 World Stem Cell Summit (WSCS).