Janet Lambert, MBA, Alliance for Regenerative Medicine (ARM), Washington, DC, outlines the key themes and discussions that will be presented at the 2020 Meeting on the Mesa. Such insights include the realities of bringing gene therapies to market, the technologies that will disrupt cell therapy, cell and gene therapies for chronic conditions, and a special session on the challenges related to commercialization. This interview took place during the 2020 Meeting on the Mesa congress.