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TERMIS 2021 | Elucidating mechanisms of hearing loss with iSPCs

Brigitte Malgrange, Pharm.D, PhD, University of Liège, Liège, Belgium, describes ongoing research to develop organoids and bioassays for researching hereditary hearing loss. Over 100 genes are implicated in hereditary hearing loss and sourcing induced pluripotent stem cells (iSPCs) derived from fibroblasts are important to determine the mechanisms of the disease. Dr Malgrange additionally highlights the possibility of developing regenerative therapies as a result of the aforementioned research conducted. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).