Ruud Das, PhD, Scinus Cell Expansion, Bilthoven, The Netherlands, discusses strategies to scale up the manufacturing of cell therapies. Dr Das highlights the need for automated bioreactors to successfully produce cell therapies on a commercial scale, and discusses additional factors that need to be considered by potential manufacturers. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).