CAR-T Meeting 2023 | Challenges with CAR-T therapy in AML & insights into IF-BETTER-gated CAR-T cells

Sascha Haubner, MD, Memorial Sloan Kettering Cancer Center, New York, NY, discusses challenges with developing efficacious CAR-T cell products for the treatment of patients with acute myeloid leukemia (AML), highlighting the heterogeneity of this disease. Dr Haubner then shares some insights into the development of IF-BETTER-gated CAR-T cells, which have demonstrated promising pre-clinical activity and will soon be evaluated in a first-in-human trial. This interview took place at the EBMT-EHA 5th European CAR T-cell Meeting held in Rotterdam, The Netherlands.

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