Suradip Das, PhD, University of Pennsylvania, Philadelphia, PA, discusses issues relating to tissue-engineered treatments for volumetric muscle loss (VML). Finding the optimal conditions for co-culturing myocytes and motor neurons, which are both necessary for muscle growth, is an important consideration, as well as developing strategies to have animal models with similar levels of VML. Dr Das additionally comments on the potential use of induced pluripotent stem cells, and clinically relevant delayed repair models in an in vivo setting. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).
Dr Das reports that the concept of Innervation in engineering artificial tissues and organs is protected by PCT application – PCT/US2019/060585.