Beatriz Fernández-Muñoz, PhD, Andalusian Network of Design and Translation of Advanced Therapies, Seville, Spain, describes the remaining challenges associated with the cryopreservation of cell therapy products, which facilitates the distribution of cell therapies and can reduce manufacturing costs. Dr Fernández-Muñoz discusses the need to improve cryopreservation techniques to enhance cell recovery after thawing, maintain cell potency and reduce the use of dimethyl sulfoxide (DMSO) given its toxicity. This interview took place at the International Society for Stem Cell Research (ISSCR) 2021 Annual Meeting.