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TERMIS 2021 | Spatially patterned scaffolds in vascular regeneration

Ngan Huang, PhD, Stanford University, Stanford, CA, discusses how vascular systems can be regenerated with collagen scaffolds. Extruded collagen scaffolds can be stacked on top of each other to support vascularization in muscle cells, and in myocytes with the spatially aligned scaffold, longer myotubes were formed, which enabled more successful and organized muscle regeneration. Scaffold orientation additionally influenced muscle growth by stimulating the release of pro-angiogenic growth factors in endothelial cells. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).